introduction: MDD overview
Understanding the impact of depression
Depression affects millions of people. But every patient with depression responds to treatment differently. For healthcare professionals seeking treatment options for their patients, Viibryd® is approved for the treatment of major depressive disorder (MDD) in adults.
Depression affects many…
- MDD is the #1 contributor to disability worldwide1
- MDD is the most common mental illness in the U.S., affecting almost 16 million adults2,3
In many different ways…
- MDD is a heterogeneous disease—every patient can present with different symptoms4
- Persistent depressed mood or loss of interest are common defining features of MDD4*
- Other MDD symptoms are also persistent and vary by patient4*
- Insomnia or hypersomnia
- Weight gain or weight loss; increase or decrease in appetite
- Psychomotor agitation or psychomotor retardation
- Fatigue or loss of energy
- Feelings of worthlessness or excessive/inappropriate guilt
- Diminished ability to think/concentrate or indecisiveness
- Recurrent thoughts of death/suicide or suicide attempt
MDD diagnosis requires 5 (or more) of the symptoms listed above, which must be present for at least 2 weeks, and represent a change from previous functioning. At least one of the symptoms must be either depressed mood or loss of interest or pleasure.4
Unmet needs still exist
According to the National Institute of Mental Health:
In the STAR*D Study
- World Health Organization. The global burden of disease, 2004 update. Geneva, Switzerland: WHO Press, World Health Organization; 2008.
- Mental health basics. Centers for Disease Control and Prevention website. http://www.cdc.gov/mentalhealth/basics.htm. Updated October 4, 2013. Accessed September 1, 2016.
- The NSDUH Report. Rockville, MD: Substance Abuse and Mental Health Services Administration, Office of Applied Studies; January 3, 2008. http://www.samhsa.gov/data/2k8/depression/depressionTX.pdf. Accessed September 1, 2016.
- American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Washington, DC: American Psychiatric Association; 2013.
- National Institute of Mental Health website. Major depressive disorder among adults. http://www.nimh.nih.gov/health/statistics/prevalence/major-depression-among-adults.shtml. Accessed September 1, 2016.
- Trivedi MH, Rush AJ, Wisniewski SR, et al. Am J Psychiatry. 2006;163:28-40.
- American Psychiatric Association. Practice guideline for the treatment
of patients with major depressive disorder. Third edition.
guidelines/guidelines/mdd.pdf. Published November 2010. Accessed September 1, 2016.